HIF-2α-IN-4
Cat. No.: DC47980
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Chemical Structure
882268-69-1
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Field of application
HIF-2α-IN-4 is a potent inhibitor of hypoxia inducible factor-2α (HIF-2α) translation, with an IC50 of 5 μM. HIF-2α-IN-4 decreases both constitutive and hypoxia-induced HIF-2α protein expression. HIF-2α-IN-4 links its 5'UTR iron-responsive element to oxygen sensing.
| Cas No.: |
882268-69-1 |
| Chemical Name: |
HIF-2α-IN-4 |
| Synonyms: |
HIF-2a Translation Inhibitor 76;HIF-2a translation inhibitor;HIF-2α-IN-4;Methyl 3-[[cyano(methylsulfonyl)methylene]hydrazinyl]-2-thiophenecarboxylate (ACI);HIF-2;882268-69-1;Methyl 3-(([cyano(methanesulfonyl)methylidene]amino)amino)thiophene-2-carboxylate;SR-01000635592-1;HY-136748;HIF-2alpha-IN-4;SCHEMBL781448;CCG-45847;MS-24103;A-IN-4;CS-0133535;methyl 3-[(2E)-2-[cyano(methylsulfonyl)methylidene]hydrazinyl]thiophene-2-carboxylate;DA-64162;methyl 3-(2-(cyano(methylsulfonyl)methylene)hydrazineyl)thiophene-2-carboxylate;HMS554D20 |
| SMILES: |
N#CC(S(C)(=O)=O)=NNC1=C(C(OC)=O)SC=C1 |
| Formula: |
C9H9N3O4S2 |
| M.Wt: |
287.315459012985 |
| Purity: |
98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
MSDS
| TITLE |
DOWNLOAD |
| MSDS_31860_DC47980_882268-69-1 |
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COA
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