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DS-1001b

  Cat. No.:  DC28576   Featured
Chemical Structure
1898207-64-1
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More than 5000 active chemicals with high quality for research!
Field of application
DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity.
Cas No.: 1898207-64-1
SMILES: CC1=CN(C2=CC=CC(=C12)/C=C/C(=O)O)C(=O)C3=C(ON=C3C4=C(C=C(C=C4Cl)Cl)Cl)C(C)(C)F.CC(C)(C)N
Formula: C29H29Cl3FN3O4
M.Wt: 608.92
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity[1].
Target: IDH-1[1]
References: [1]. Zhao Yizhaiteng, et al. Isoxazole derivative as mutated isocitrate dehydrogenase 1 inhibitor. WO2016052697A1.
MSDS
TITLE DOWNLOAD
MSDS_12628_DC28576_1898207-64-1
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
DC44726 Enasidenib Mesylate Enasidenib (Idhifa, AG-221) mesylate is an orally available, selective and potent inhibitor of mutant isocitrate dehydrogenase 2 (IDH2).
DC28576 DS-1001b DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity.
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