Deruxtecan
Cat. No.: DC50025
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Chemical Structure
1599440-13-7
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Field of application
Deruxtecan, a topoisomerase I inhibitor, is an exatecan derivative (DX-8951 derivative) with a cleavable pepetide linker and a maleimide group. The maleimide group in Deruxtecan can react with antibody to form antibody-drug conguates (ADC) such as Trastuzumab deruxtecan (DS-8201a), which is a HER2-targeting antibody–drug conjugate.
Cas No.: |
1599440-13-7 |
Chemical Name: |
Deruxtecan |
Synonyms: |
Deruxtecan;5SEB972CO4;Deruxtecan [USAN];Mc-ggfg-dxd(1);N-(6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl)glycylglycyl-L-phenylalanyl- |
SMILES: |
FC1=CC2=C3C(=C1C)CC[C@@H](C3=C1C(C3=CC4[C@](C(=O)OCC=4C(N3C1)=O)(CC)O)=N2)NC(COCNC(CNC([C@H](CC1C=CC=CC=1)NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)=O)=O)=O |
Formula: |
C52H56FN9O13 |
M.Wt: |
1034.05195617676 |
Purity: |
98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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