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Docetaxal

  Cat. No.:  DC41160  
Chemical Structure
125354-16-7
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More than 5000 active chemicals with high quality for research!
Field of application
Docetaxal (10-Acetyl docetaxel; PNU-101383), an analog of Docetaxel, is a microtubule disassembly inhibitor, with antimitotic activity. Docetaxal has cytotoxicity for murine leukemic cells.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 125354-16-7
Chemical Name: 10-Acetyl Docetaxel
Synonyms: Docetaxel;DOCETAXOL;N-Debenzoyl-N-(tert-butoxycarbonyl)taxol;10-Acetyldocetaxel;10-Acetyltaxotere;Docetaxal;PNU 101383;ACETYLDOCETAXEL, 10-(P);DOCETAXEL TRIHYDRATE;Docetaxel impurity G;Docetaxel N-Debenzoyl-N-(tert-butoxycarbonyl)taxol;Eltrombopag Impurity 2
SMILES: CC1=C2[C@@H](OC(C)=O)C([C@@]3([C@@H](O)C[C@@H]4[C@@]([C@H]3[C@H](OC(C5=CC=CC=C5)=O)[C@](C2(C)C)(O)C[C@@H]1OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)C6=CC=CC=C6)=O)(OC(C)=O)CO4)C)=O
Formula: C45H55NO15
M.Wt: 849.9
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_24173_DC41160_125354-16-7
COA
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Cat. No. Product name Field of application
DC73247 FiVe1 FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase, causes mitotic catastrophe, multinucleation, and the loss of stemness in cancer cells.
DC71742 MY-875 MY-875 is a competitive microtubulin polymerization inhibitor with an IC50 value of 0.92 μM. MY-875 inhibits microtubulin polymerization by targeting colchicine binding sites and activates the Hippo pathway. MY-875 induces apoptosis and has anticancer activity.
DC49574 SB-216 SB-216 is a potent tubulin polymerization inhibitor. SB-216 shows strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, lung cancer, and breast cancer.  SB-216 can be used for cancer research.
DC48439 Verubulin hydrochloride Verubulin hydrochloride(MPC 6827 hydrochloride) is a microtubule destabilizer and vascular disrupting agent that achieve high brain concentration relative to plasma in animals.
DC47191 Sovilnesib(AMG-650) Sovilnesib(AMG650) is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.
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DC41160 Docetaxal Docetaxal (10-Acetyl docetaxel; PNU-101383), an analog of Docetaxel, is a microtubule disassembly inhibitor, with antimitotic activity. Docetaxal has cytotoxicity for murine leukemic cells.
DC40078 MAP4343 MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents.
DC28956 Valecobulin hydrochloride Valecobulin hydrochloride (CKD-516 hydrochloride) is a valine prodrug of S516 and a vascular disrupting agent (VDA). Valecobulin hydrochloride is a potent β-tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors.
DC5882 Fosbretabulin disodium Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis.
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