Dofetilide (Tikosyn)|cas 115256-11-6|supplier DC Chemicals

Cas No.:	115256-11-6
Chemical Name:	Tikosyn, UK68798
Synonyms:	Tikosyn, UK68798
SMILES:	CS(NC1=CC=C(CCN(C)CCOC2=CC=C(NS(C)(=O)=O)C=C2)C=C1)(=O)=O
Formula:	C₁₉H₂₇N₃O₅S₂
M.Wt:	441.56
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Dofetilide(Tikosyn) is a class III antiarrhythmic agent.In patients with congestive heart failure and reduced left ventricular function, dofetilide was effective in converting atrial fibrillation, preventing its recurrence, and reducing the risk of hospitalization for worsening heart failure. Dofetilide had no effect on mortality [1]. dofetilide preferentially blocks open (or activated) channels and that the fast inactivation may competitively slow the binding kinetics. Dofetilide acts as a slow-onset/slow-offset open channel blocker of this current at nanomolar concentrations [2].

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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