Cas No.: | 1141934-97-5 |
Chemical Name: | ACU4429,ACU 4429,ACU-4429 |
Synonyms: | ACU4429,ACU 4429,ACU-4429 |
SMILES: | O[C@@H](C1=CC=CC(OCC2CCCCC2)=C1)CCN.[H]Cl |
Formula: | C16H26ClNO2 |
M.Wt: | 299.84 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM.Emixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration.[2] |