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Fludarabine triphosphate

  Cat. No.:  DC41008  
Chemical Structure
74832-57-8
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More than 5000 active chemicals with high quality for research!
Field of application
Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate, inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 74832-57-8
Chemical Name: 9H-Purin-6-amine,2-fluoro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-b-D-arabinofuranosyl]-
SMILES: OP(=O)(O)OP(=O)(O)OP(=O)(O)OCC1C(O)C(O)C(O1)N2C3C(N=C2)=C(N)N=C(F)N=3
Formula: C10H15N5O13FP3
M.Wt: 525.1716
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_24021_DC41008_74832-57-8
COA
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Cat. No. Product name Field of application
DC73210 TH7528 TH7528 is a SAMHD1 inhibitor with IC50 of 4.5 μM/2.8 μM/2.6 μM against dGTP/Cl-F-ara-ATP/ara-CTP, respectively.
DC73203 DI-87 DI-87 ((R)-DI-87) is a highly potent, specific, orally bioavailable deoxycytidine kinase (dCK) inhibitor with IC50 of 3.15 nM.
DC72019 Fludarabine triphosphate trisodium Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine, is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
DC44975 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
DC41008 Fludarabine triphosphate Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate, inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
DC7762 RX-3117 RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity.
DC73208 PSB-0963 PSB-0963 (PSB0963) is a potent, selective ecto-5'-Nucleotidase (eN, CD73) inhibitor with Ki of 150 nM, >100-fold selectivity over NTPDases.
DC73207 PSB-0952 PSB-0952 (PSB0952) is a potent, selective ecto-5'-Nucleotidase (eN, CD73) inhibitor with Ki of 260 nM, >150-fold selectivity over NTPDases and P2Y receptor subtypes P2Y2, P2Y4, P2Y6, and P2Y12.
DC73206 PSB-071 PSB-071 (PSB071) is a small molecule inhibitor of nucleoside triphosphate diphosphohydrolases (NTPDase).
DC73205 JLT048 JLT048 is a small molecule inhibitor of tyrosyl-DNA-phosphodiesterases 1 and 2 (TDP1 and TDP2) with IC50 of 7.7 and 32 uM, respectively.
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