Cas No.: | 200484-11-3 |
Chemical Name: | 2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine |
Synonyms: | CHS 828;CHS-828;GMX1778;GMX-1778;N-Cyano-N'-(4-nitrophenyl)thiourea;N-cyano-N'-(6-(p-chlorophenoxy)hexyl)-N"-(4-pyridyl)guanidine;Thiourea,N-cyano-N'-(4-nitrophenyl);N-[6-(4-Chlorophenoxy)hexyl]-N′-cyano-N′′-4-pyridinyl-guanidine;GMX 1778;CHS828;GMX1778 (CHS828);8LAP87DNSZ;2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine;Guanidine, N-[6-(4-chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinyl-;N-Cyano-N'-(6-(p-chlorophenoxy)hexyl)-N'-(4-pyridyl)guanidine;Guanidine, N-(6-(4-chlorophenoxy)hexyl)-N'-cyano-N''-4-pyridinyl-;BDBM81396 |
SMILES: | ClC1C([H])=C([H])C(=C([H])C=1[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/N=C(\N([H])C#N)/N([H])C1C([H])=C([H])N=C([H])C=1[H] |
Formula: | C19H22ClN5O |
M.Wt: | 371.8639 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | GMX1778(CHS-828) is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM. |