GPR40 Activator 1

  Cat. No.:  DC42321  
Chemical Structure
1309435-60-6
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More than 5000 active chemicals with high quality for research!
Field of application
GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.
Cas No.: 1309435-60-6
Chemical Name: GPR40 Activator 1
SMILES: OC(C[C@H](C#CC)C(C=C1)=CC=C1OCC2=CC=C(CN3CCC4(C=CC5=C4C=CC=C5)CC3)S2)=O
Formula: C31H31NO3S
M.Wt: 497.65
Sotrage: Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
MSDS
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MSDS_25928_DC42321_1309435-60-6
COA
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Cat. No. Product name Field of application
DC44150 HWL-088 HWL-088 is a highly potent and orally active free fatty acid receptor 1 (FFA1/GPR40) agonist (EC50 of 18.9 nM) with moderate PPARδ activity (EC50 of 570.9 nM) . HWL-088 improves glucose and lipid metabolism, and has anti-diabetic effects.
DC42321 GPR40 Activator 1 GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.
DC28968 TUG-424 TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity.
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