GSK2606414
Cat. No.: DC7142
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Chemical Structure
1337531-36-8
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Field of application
GSK2606414 is an orally available, potent, and selective PERK inhibitor with an IC50 of 0.4 nM.
| Cas No.: |
1337531-36-8 |
| Chemical Name: |
7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyrimidin-4-amine |
| Synonyms: |
GSK2606414,GSK-2606414,GSK 2606414 |
| SMILES: |
C1=CC(C2C3C(N)=NC=NC=3N(C)C=2)=CC2CCN(C(=O)CC3=CC=CC(C(F)(F)F)=C3)C1=2 |
| Formula: |
C24H20F3N5O |
| M.Wt: |
451.44 |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
GSK2606414 is a cell-permeable and orally available PERK inhibitor with an IC50 of 0.4 nM. |
| In Vivo: |
GSK2606414 (50 and 150 mg/kg, p.o.) inhibits the growth of a human tumor xenograft in mice[1]. |
| In Vitro: |
GSK2606414 inhibits PERK activation in cells[1]. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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