Gemcitabine monophosphate

  Cat. No.:  DC10590   Featured
Chemical Structure
1638288-31-9
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Field of application
Gemcitabine monophosphate disodium salt, also called GemMP, is a monophosphate derivative of Gemcitabine.
Cas No.: 1638288-31-9
Synonyms: Gemcitabine monophosphate disodium salt monohydrate; Gemcitabine monophosphate disodium; GemMP
SMILES: O=C1N=C(N)C=CN1[C@@H]2O[C@H](COP(O[Na])(O[Na])=O)[C@@H](O)C2(F)F.O
Formula: C9H12F2N3Na2O8P
M.Wt: 405.158
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Gemcitabine monophosphate disodium salt, also called GemMP, is a monophosphate derivative of Gemcitabine. Gemcitabine (Gem) is a deoxycytidine analog that is effective against pancreatic cancer and other malignancies following conversion to the 5'-O-mono-, di- and tri-phosphate forms. GemMP decreased tumor cell growth at concentrations ranging from 1 to 50 nM. GemMP is a potent cytotoxic agent that serves to induce apoptosis in association with increased Fas expression in cultured thyroid cancer cell lines.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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