JHU-083

  Cat. No.:  DC11230   Featured
Chemical Structure
1998725-11-3
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Field of application
JHU-083 is a Glutamine antagonist, a DON prodrug.
Cas No.: 1998725-11-3
Chemical Name: ethyl (S)-2-((S)-2-amino-4-methylpentanamido)-6-diazo-5-oxohexanoate
Synonyms: JHU083;JHU 083
SMILES: C(OCC)(=O)[C@H](NC(=O)[C@H](N)CC(C)C)CCC(=O)C=[N+]=[N-]
Formula: C14H24N4O4
M.Wt: 312.37
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
Description: JHU-083 inhibits increased glutaminase activity in isolated CD11b+ cells, but not other cells in the prefrontal cortex and hippocampus of mice subjected to CSDS. JHU-083 suppresses CSDS-induced upregulation of proinflammatory cytokines in CD11b+ cells. [1
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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