Cas No.: | 1998725-11-3 |
Chemical Name: | ethyl (S)-2-((S)-2-amino-4-methylpentanamido)-6-diazo-5-oxohexanoate |
Synonyms: | JHU083;JHU 083 |
SMILES: | C(OCC)(=O)[C@H](NC(=O)[C@H](N)CC(C)C)CCC(=O)C=[N+]=[N-] |
Formula: | C14H24N4O4 |
M.Wt: | 312.37 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Description: | JHU-083 inhibits increased glutaminase activity in isolated CD11b+ cells, but not other cells in the prefrontal cortex and hippocampus of mice subjected to CSDS. JHU-083 suppresses CSDS-induced upregulation of proinflammatory cytokines in CD11b+ cells. [1 |