I3MT-3
Cat. No.: DC40375
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Chemical Structure
459420-09-8
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Field of application
I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM) and is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
Cas No.: |
459420-09-8 |
Chemical Name: |
I3MT-3 |
Synonyms: |
4-Methyl-2-(2-Naphthalen-1-Yl-2-Oxidanylidene-Ethyl)sulfanyl-1~{h}-Pyrimidin-6-One;I3MT-3;GTPL10210;compound 3 [PMID: 28079151];4-methyl-2-(2-naphthalen-1-yl-2-oxoethyl)sulfanyl-1~{H}-pyrimidin-6-one;6-Methyl-2-((2-(naphthalen-1-yl)-2-oxoethyl)thio)pyrimidin-4(3H)-one;7NC;HMPSNE;starbld0000913;2-[(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(naphthalen-1-yl)ethan-1-one;ZINC04370000;G17644;6-methyl-2-{[2-(naphthalen-1-yl)-2-oxoethyl]sulfanyl}-3H-pyrimidin-4-one;6-methyl-2-{[2-(naphthalen-1-yl)-2-oxoethyl]sulfanyl}-1H-pyrimidin-4-one;CS-0095460;AB00682589-01;HY-128206;4-methyl-2-(2-naphthalen-1-yl-2-oxoethyl)sulfanyl-1H-pyrimidin-6-one;459420-09-8;MS-24517;AKOS002376100;CHEMBL5092608;s3541;DA-54208 |
SMILES: |
S(C1=NC(C)=CC(N1)=O)CC(C1=CC=CC2C=CC=CC1=2)=O |
Formula: |
C17H14N2O2S |
M.Wt: |
310.370262622833 |
Purity: |
98% |
Sotrage: |
Please store the product under the recommended conditions in the Certificate of Analysis. |
MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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