Cas No.: | 99011-02-6 |
SMILES: | CC(CN1C=NC2C(=NC3C=CC=CC=3C1=2)N)C |
Formula: | C14H16N4 |
M.Wt: | 240.3 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Imiquimod is an immune response modifier and a toll-like receptor 7 agonist. |
In Vivo: | In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1]. |