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L-798106

  Cat. No.:  DC28977   Featured
Chemical Structure
244101-02-8
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More than 5000 active chemicals with high quality for research!
Field of application
L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has  micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM at EP4, EP1 and EP2, respectively.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 244101-02-8
Chemical Name: 2-Propenamide, N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phen yl]-, (2E)-
Synonyms: 2-Propenamide, N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phen yl]-, (2E)-;L-798106;N-(5-bromo-2-methoxyphenyl)sulfonyl-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide;(2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide;N-[(5-BroMo-2-Methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylMethyl)phenyl]-2-propenaMide;Zinterol hydrochloride
SMILES: COC1C=CC(Br)=CC=1S(NC(/C=C\C1=CC=CC=C1CC1C=CC2=CC=CC=C2C=1)=O)(=O)=O
Formula: C27H22BrNO4S
M.Wt: 536.436885356903
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM at EP4, EP1 and EP2, respectively[1].
Target: Ki values: 0.3 nM (EP3 receptor); 916 nM (EP4 receptor); > 5000 nM (EP1/2 receptor)[1]
References: [1]. Juteau H, et al. Structure-activity relationship of cinnamic acylsulfonamide analogues on the human EP3 prostanoid receptor. Bioorg Med Chem. 2001 Aug;9(8):1977-84.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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