Cas No.: | 2055050-87-6 |
Chemical Name: | 8-chloro-2,5-dihydro-2-(3-methoxyphenyl)-3H-pyrazolo[4,3-c]quinolin-3-one |
SMILES: | ClC1C=CC2NC=C3C(=O)N(C4C=CC=C(OC)C=4)N=C3C=2C=1 |
Formula: | C17N3O2ClH12 |
M.Wt: | 325.7491 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM[1]. |
References: | [1]. Varagic Z, et al. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. Br J Pharmacol. 2013 May;169(2):371-83. |