DC11363 |
NSC 185058
|
NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy. |
DC9702 |
MRT68921
|
MRT68921 is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. |
DC9496 |
HG-10-102-01
|
HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2(IC50=23.3 nM) and the G2019S mutant(IC50=3.2 nM)
|
DC10778 |
YKL-06-061
|
YKL-06-061 is a potent and selective SIK (salt-inducible kinase) inhibitor. |
DC12501 |
WNK-IN-11
|
WNK-IN-11 is a potent, selectiive and orally active inhibitor of WNK1 kinase. |
DC9883 |
WNK463
|
WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activity of all four WNK family members (WNK1, WNK2, WNK3, and WNK4). |
DC10378 |
Urolithin A
|
Urolithin A is an intestinal metabolite of ellagic acid with antioxidant and antiproliferative effects; inhibits T24 and Caco-2 cell growth with IC50 values of 43.9 and 49 μM, respectively. |
DC10456 |
STF-62247
|
STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM). |
DC9696 |
SMER28
|
SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells when supplied at 47 µM. |
DC8316 |
SBI-0206965
|
SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor. |