YKL-06-061

  Cat. No.:  DC10778   Featured
Chemical Structure
2172617-15-9
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More than 5000 active chemicals with high quality for research!
Field of application
YKL-06-061 is a potent and selective SIK (salt-inducible kinase) inhibitor.
Cas No.: 2172617-15-9
Chemical Name: 1-Cyclobutyl-3-(2,6-dimethylphenyl)-7-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one
Synonyms: YKL-06-061; YKL06-061; YKL 06-061; YKL-06061; YKL06061; YKL 06061
SMILES: O=C1N(C2CCC2)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6C
Formula: C30H37N7O2
M.Wt: 527.3
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC10778 YKL-06-061 YKL-06-061 is a potent and selective SIK (salt-inducible kinase) inhibitor.
DC10824 ARN-3236 ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L.
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