Leupeptin hemisulfate

  Cat. No.:  DC8688   Featured
Chemical Structure
103476-89-7
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More than 5000 active chemicals with high quality for research!
Field of application
Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor, which has been shown to inhibit cathepsins B, H, L, and S, calpain, and trypsin. Leupeptin hemisulfate is an orally active, antioxidant and anti-inflammatory agent.
Cas No.: 103476-89-7
Chemical Name: (S)-2-acetamido-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)-N-((S)-5-guanidino-1-oxopentan-2-yl)-4-methylpentanamide hemisulfate
Synonyms: Leupeptin hemisulfate anhydrous; NK-381; NK 381; NK381;
SMILES: OS(=O)(O)=O.N/C(=N/CCCC(NC(C(NC(C(NC(=O)C)CC(C)C)=O)CC(C)C)=O)C=O)/N.N/C(=N/CCCC(NC(C(NC(C(NC(=O)C)CC(C)C)=O)CC(C)C)=O)C=O)/N
Formula: C40H78N12O12S
M.Wt: 951.19
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC46395 Z-FY-CHO Z-FY-CHO (Z-Phe-Tyr-CHO) is a potent and specific cathepsin L (CTSL) inhibitor.
DC28152 SID 26681509 SID 26681509 is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM. SID 26681509 inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC50s of 15.4 μM and 12.5 μM, respectively. SID 26681509 shows no inhibitory activity against cathepsin G.
DC8688 Leupeptin hemisulfate Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor, which has been shown to inhibit cathepsins B, H, L, and S, calpain, and trypsin. Leupeptin hemisulfate is an orally active, antioxidant and anti-inflammatory agent.
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