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Liothyronine sodium

  Cat. No.:  DC9188   Featured
Chemical Structure
55-06-1
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Field of application
Liothyronine sodium (T3 Sodium sal) is the most potent form of thyroid hormone used to treat hypothyroidism and myxedema coma.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 55-06-1
Chemical Name: sodium (S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
Synonyms: Liothyronine; Triiodothyronine; 3,3',5-Triiodo-L-thyronine; Liothyronin; Tresitope; 3,5,3'-triiodothyronine; Cytomel; Tertroxin
SMILES: O=C([O-])[C@@H](N)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1.[Na+]
Formula: C15H11I3NNaO4
M.Wt: 672.96
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: 3,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.
In Vitro: 3,3',5-Triiodo-L-thyronine (T3, 100 nM) stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. 3,3',5-Triiodo-L-thyronine binds to human β1 thyroid hormone receptor (hTRβ1), and change its conformation. 3,3',5-Triiodo-L-thyronine promotes growth, induces differentiation and regualtes metabolic effects[2].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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