Losartan

  Cat. No.:  DCAPI1419  
Chemical Structure
114798-26-4
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More than 5000 active chemicals with high quality for research!
Field of application
Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II.
Cas No.: 114798-26-4
SMILES: ClC1=C(CO)N(CC2=CC=C(C(C=CC=C3)=C3C4=NN=NN4)C=C2)C(CCCC)=N1
Formula: C22H23ClN6O
M.Wt: 422.91
Purity: >99%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: For the detailed information of Losartan, the solubility of Losartan in water, the solubility of Losartan in DMSO, the solubility of Losartan in PBS buffer, the animal experiment(test) (test) of Losartan, the cell expriment (test) of Losartan, the in vivo, in vitro and clinical trial test of Losartan, the EC50, IC50,and Affinity of Losartan,, please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DCAPI1452 Valsartan Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist with an IC50 ranging from 39.5 to 116 μM. This in turn causes blood vessel dilation.
DC9179 Olmesartan MedoxoMil Olmesartan medoxomil(Olmetec; Benicar; CS 866) is an angiotensin II receptor antagonist which is used as an anti-hypertensive.
DCAPI1464 Olmesartan Olmesartan Acid is an angiotensin II receptor antagonist that prevents the binding of angiotensin II, thus preventing vasoconstriction.
DCAPI1419 Losartan Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II.
DC9142 Candesartan Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.
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