DC9602 |
Balaglitazone
|
Balaglitazone (DRF-2593; NN-2344) is a novel partial agonist of PPAR-γ. |
DC7412 |
R(+)-Etomoxir (sodium salt)
|
A PPARα agonist and an irreversible CPT-1 inhibitor. |
DC1034 |
WY14643 (Pirinixic Acid)
|
WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with ED50 of 1.5 μM. |
DC10700 |
Seladelpar
|
Seladelpar is a selective peroxisome proliferator-activated receptor (SPPAR) -δ receptor agonist. |
DC12034 |
MA-0204
|
MA-0204 is a potent, selective PPARδ modulator with good pharmacokinetic properties. |
DC2079 |
GW-9662
|
GW9662 is a selective PPAR antagonist, inhibiting PPARγ, PPARα and PPARδ with IC50 of 3.3 nM, 32 nM and 2 μM, respectively. |
DC4233 |
GW501516
|
GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes. |
DC9904 |
GW0742
|
GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively. |
DC2078 |
GW-7647
|
GW 7647 is a potent PPARα agonist with 200-fold selectivity over PPARγ and PPARδ. |
DC1035 |
GSK3787
|
GSK3787 is as a potent and selective antagonist of PPARδ with pIC50 of 6.6. |