MK 886|cas 118414-82-7|DC Chemicals|Price|Buy

Cas No.:	118427-55-7
Chemical Name:	1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid
Synonyms:	L-663,536,MK-886,MK 886,MK886
SMILES:	CC(C)(C([O-])=O)CC1=C(SC(C)(C)C)C2=CC(C(C)C)=CC=C2N1CC3=CC=C(Cl)C=C3.[Na+]
Formula:	C₂₇H₃₃ClNO₂Sna
M.Wt:	494.1
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

An inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes). Acts by inhibiting 5-lipoxygenase-activating protein (FLAP) (IC50 = 30 nM for inhibition of [125I]-L-691,678 photoaffinity labelling). Also moderately potent PPARα antagonist (IC50 = 0.5-1 μM). Orally active in vivo.

MSDS

COA

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2018-0101

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DC26209	Papain Inhibitor	#N/A
DC11456	Chymotrypsin substrate（MeO-Suc-Arg-Pro-Tyr-pNA）	MeO-Suc-Arg-Pro-Tyr-pNA is a synthetic colorimetric peptide substrate displaying chymotrypsin-like specificity and is used in the measurement of Kallikreins. It is succinylated at N-terminus and has a nitroanilide tag at the C-terminus.
DC24032	PTP1B-IN-1	A 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for design of protein tyrosine phosphatase-1B (PTP1B) inhibitor.
DC11230	JHU-083	JHU-083 is a Glutamine antagonist, a DON prodrug.
DC8050	Akt Inhibitor IV	Akt Inhibitor IV is n Inhibitor of Akt protein kinase
DC9240	PS-47

MK-886 (sodium salt)