MPC-3100

Cas No.:	958025-66-6
Chemical Name:	(2S)-1-[4-[2-[6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]purin-9-yl]ethyl]piperidin-1-yl]-2-hydroxypropan-1-one
Synonyms:	MPC3100,MPC 3100
SMILES:	NC1=C2C(N(CCC3CCN(C([C@@H](O)C)=O)CC3)C(SC4=C(Br)C=C(OCO5)C5=C4)=N2)=NC=N1
Formula:	C22H25BrN6O4S
M.Wt:	549.4407
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

MPC-3100 is a fully synthetic potent small-molecule Hsp90 inhibitor (IC50 of 60 nM). MPC-3100 causes HCT-116, NCI-N87 and DU-145 cells to result in a time-dependent reduction in client protein levels with maximal reduction by 24 hours. The IC50 values For client protein reduction ranges from 0.1 mM to 0.5 mM, comparable to the cellular cytotoxicity values of MPC-3100 at 72 hours For the various cell lines.For the detailed information of MPC-3100, the solubility of MPC-3100 in water, the solubility of MPC-3100 in DMSO, the solubility of MPC-3100 in PBS buffer, the animal experiment (test) of MPC-3100, the cell expriment (test) of MPC-3100, the in vivo, in vitro and clinical trial test of MPC-3100, the EC50, IC50,and Affinity of MPC-3100, Please contact DC Chemicals.