Mexiletine Hydrochloride

Cas No.:	5370-01-4
Chemical Name:	Mexiletine hydrochloride
Synonyms:	1-(2,6-dimethylphenoxy)-2-propanamine hydrochloride;1-Methyl-2-(2,6-xyloxy)ethylamine hydrochloride;Katen;Mexiletine hydrochloride;Mexitil;Ritalmex;Mexiletine (hydrochloride);Mexiletine HCl;1-(2,6-Dimethylphenoxy)-2-propylamine Hydrochloride;Cirumimeru;Ko 1173Cl;ko1173;Mexilitene;MEXILITINE HCL;Olzoron;Toy;1-(2,6-Xylyloxy)-2-aminopropane hydrochloride;Mexiletene hydrochloride;1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride;2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride;Ko 1173 Cl;KO 1173;(S)-1-(2,6-Dimethylphenoxy)propan-2-amine hydrochloride;DSSTox_RID_81125;DSSTox_CID_25783;DSSTox_GSID_45783;1-Methyl-2-(
SMILES:	Cl.CC(N)COC1=C(C)C=CC=C1C
Formula:	C11H18ClNO
M.Wt:	215.7197
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Mexiletine hydrochloride is a non-selective voltage-gated sodium channel blocker; Class IB anti-arrhythmic compound.

References:

[1]. Desaphy JF, et al. Effect of mexiletine on sea anemone toxin-induced non-inactivating sodium channels of rat skeletal muscle: a model of sodium channel myotonia. Neuromuscul Disord. 1999 May;9(3):182-9. [2]. Mori K, et al. Inhibitory effects of class I and IV antiarrhythmic drugs on the Na+-activated K+ channel current in guinea pig ventricular cells. Naunyn Schmiedebergs Arch Pharmacol. 1998 Dec;358(6):641-8.