Cas No.: | 589-68-4 |
Chemical Name: | 2,3-Dihydroxypropyl tetradecanoate |
Synonyms: | 2,3-Dihydroxypropyl tetradecanoate;Tetradecanoic acid,2,3-dihydroxypropyl ester;Myristic acid 1-monoglyceride;α-Monomyristin;Monomyristin;1-Monomyristoyl Glycerol;1-Monotetradecanoyl-rac-glycerol;rac-1-Myristoylglycerol;DL-α-Myristin;Glycerol α-Monomyristate;1-Monomyristin;Rac-Glycerol-1-myristate;1-Myristoyl-rac-glycerol;Glyceryl monomyristate;Glyceryl myristate;Myristin, 1-mono-;Glycerol monomyristate;DL--Myristin;Tetradecanoic acid, 2,3-dihydroxypropyl ester;2,3-Dihydroxypropyl myristate;Glycerol 1-myristate;.alpha.-Monomyristin;rac-Glycerol 1-myristate;DCBSHORRWZKAKO-UHFFFAOYSA-N;Tetradecanoic acid, monoester with 1, |
SMILES: | CCCCCCCCCCCCCC(=O)OCC(O)CO |
Formula: | C17H34O4 |
M.Wt: | 302.4495 |
Purity: | >98%, Standard References Grade |
Sotrage: | 4°C for 1 year, -20°C for more than 2 years |
Description: | Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3]. |
Target: | IC50: 18 μM (FAAH)[2] |
References: | [1]. Shimada H, et al. Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens). J Nat Prod. 1997 Apr;60(4):417-8. [2]. Vandevoorde S, et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochem Biophys Res Commun. 2005 Nov 11;337(1):104-9. [3]. Jumina, et al. Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents. Molecules. 2018 Nov 29;23(12). pii: E3141 |