Mycro-3

  Cat. No.:  DC10606   Featured
Chemical Structure
944547-46-0
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More than 5000 active chemicals with high quality for research!
Field of application
Mycro 3 is potent and selective for c-Myc in whole cell assays.
Cas No.: 944547-46-0
SMILES: CCOC(=O)C1=C(N(N=C1)C2=CC=CC=C2)NC(=O)C3=NN4C(=CC(=NC4=C3)C5=CC=CO5)C(F)(F)Cl
Formula: C24H17ClF2N6O4
M.Wt: 526.88
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Mycro 3 is potent and selective for c-Myc in whole cell assays.
Target: c-Myc[1]
In Vitro: Mycro 3 is potent and selective for c-Myc in whole cell assays, with weak inhibitory activity against Activator protein 1 (AP-1), Mycro 3 has a superior specificity profile to its predecessors. Mycro 3 inhibits the interaction between c-Myc and Max. Mycro 3 has high selectivity and inhibits c-Myc/Max dimerization and conjugation with DNA[1].
References: [1]. Chen BJ, et al. Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int J Biol Sci. 2014 Sep 13;10(10):1084-96.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC10606 Mycro-3 Mycro 3 is potent and selective for c-Myc in whole cell assays.
DC10617 CBL0137 CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM.
DC10075 10074-G5 10074-G5 is a c-Myc Max interaction inhibitor.
DC7575 10058-F4 10058-F4 is a c-Myc inhibitor that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression.
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