Cas No.: | 442898-34-2 |
Chemical Name: | NCGC00092410 |
SMILES: | O=C(C1CCCCC1)NC2=CC=C3N=C(N4CCOCC4)C=C(C)C3=C2 |
Formula: | C21H27N3O2 |
M.Wt: | 353.46 |
Purity: | >98% |
Sotrage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Description: | NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC), with an IC50 of 31 nM. NCGC00092410 shows no activity against the related hydrolases at concentrations up to 77 μM. NCGC00092410 is a GC chaperone and increases the activity and lysosomal localization of glucocerebrosidase in mutant cell lines. NCGC00092410 can be used for the research of Gaucher disease. |