NIBR189

  Cat. No.:  DC8836   Featured
Chemical Structure
1599432-08-2
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More than 5000 active chemicals with high quality for research!
Field of application
NIBR 189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively).
Cas No.: 1599432-08-2
Chemical Name: (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one
Synonyms: NIBR-189; NIBR 189
SMILES: BrC1=CC=C(/C=C/C(N2CCN(C(C3=CC=C(OC)C=C3)=O)CC2)=O)C=C1
Formula: C21H21BrN2O3
M.Wt: 429.31
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).NIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC8836 NIBR189 NIBR 189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively).
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