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| Cas No.: | 1811510-56-1 |
| Chemical Name: | PF-06260933 |
| Synonyms: | PF-06260933;5-(4-Chlorophenyl)-[3,3']bipyridinyl-6,6'-diamine;5-(4-Chlorophenyl)-[3,3'-bipyridine]-6,6'-diamine;TQR1219;BCP28968;BDBM50134771;s6499;PF6260933;PF06260933; PF 06260933;5-(6-aminopyridin-3-yl)-3-(4-chlorophenyl)pyridin-2-amine |
| SMILES: | ClC1C=CC(=CC=1)C1C(N)=NC=C(C2C=NC(=CC=2)N)C=1 |
| Formula: | C16H13ClN4 |
| M.Wt: | 296.75422167778 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | PF 06260933 is a potent and selective MAP4K4 inhibitor (IC50 value 3.7 nM for MAP4K4 a.k.a. HGK or ZC1) with suitable PK properties in mouse to be used as a tool in an in vivo model of diabetes, vascular inflammation and atherosclerosis. Robustly prevented TNF-α-mediated endothelial permeability in vitro, similar to MAP4K4 knockdown, and without alteration of plasma lipid content. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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