Palosuran hydrochloride

  Cat. No.:  DC42320  
Chemical Structure
2469274-58-4
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Field of application
Palosuran hydrochloride (ACT-058362 hydrochloride) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran hydrochloride can improves pancreatic and renal function in diabetic rats.
Cas No.: 2469274-58-4
Chemical Name: Palosuran hydrochloride
SMILES: OC(CC1=CC=CC=C1)(CC2)CCN2CCNC(NC3=CC(C)=NC4=CC=CC=C34)=O.[H]Cl
Formula: C25H31ClN4O2
M.Wt: 454.99
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_25927_DC42320_2469274-58-4
COA
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Cat. No. Product name Field of application
DC46233 UFP-803 TFA UFP-803 TFA is a potent urotensin-II receptor (UT) ligand. UFP-803 TFA has lower residual agonist activity, so it may be an important tool for the investigations on the role played by the UT system in physiology and pathology.
DC46232 [Orn5]-URP TFA [Orn5]-URP TFA is a potent and selective pure antagonist of Urotensin-II receptor (UT), with an pEC50 of 7.24. [Orn5]-URP TFA displays no agonist activity.
DC45292 UFP-803 UFP-803 is a potent urotensin-II receptor (UT) ligand. UFP-803 has lower residual agonist activity, so it may be an important tool for the investigations on the role played by the UT system in physiology and pathology.
DC45291 [Orn5]-URP [Orn5]-URP is a potent and selective pure antagonist of Urotensin-II receptor (UT), with an pEC50 of 7.24. [Orn5]-URP displays no agonist activity.
DC42320 Palosuran hydrochloride Palosuran hydrochloride (ACT-058362 hydrochloride) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran hydrochloride can improves pancreatic and renal function in diabetic rats.
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