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Pamoic acid disodium

  Cat. No.:  DC42122  
Chemical Structure
6640-22-8
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Field of application
Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 6640-22-8
Chemical Name: Pamoic acid disodium
SMILES: OC1=C(C(C=CC=C2)=C2C=C1C(O[Na])=O)CC(C(C=CC=C3)=C3C=C4C(O[Na])=O)=C4O
Formula: C23H14Na2O6
M.Wt: 432.33
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_25135_DC42122_6640-22-8
COA
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Cat. No. Product name Field of application
DC47035 Edaxeterkib Edaxeterkib is a potent extracellular signal-​regulated kinase (ERK) inhibitor for the research of cancer.
DC42122 Pamoic acid disodium Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect.
DC28723 ERK-IN-2 ERK-IN-2 is a potent, highly seletive and orally active ERK2 inhibitor probe with an IC50 value of 1.8 nM. ERK-IN-2 might lead to off-target toxicity and/or off-target activity at dose >10 μM.
DC10985 AZ6197 AZ6197 (AZ-6197) is a potent, selective, reversible inhibitor of ERK1/2 with IC50 of <0.3 nM (ERK2), inhibits pERK/pRSK with IC50 of 12/62 nM in A375 cells, respectively.
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