Pramipexole dihydrochloride

  Cat. No.:  DC3151  
Chemical Structure
104632-25-9
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Field of application
Pramipexole is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM.
Cas No.: 104632-25-9
SMILES: NC(S1)=NC2=C1C[C@@H](NCCC)CC2.[H]Cl.[H]Cl
Formula: C10H17N3S.2(HCl)
M.Wt: 284.25
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Pramipexole (Mirapex, Mirapexin, Sifrol) is a dopamine agonist of the non-ergoline class indicated For treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS). It is also sometimes used off-label as a treatment For cluster headache and to counteract problems with sexual dysfunction experienced by some users of selective serotonin reuptake inhibitor (SSRI) antidepressants. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated For the treatment of clinical depression and fibromyalgia. For the detailed information about the solubility of Pramipexole dihydrochloride in water, the solubility of Pramipexole dihydrochloride in DMSO, the solubility of Pramipexole dihydrochloride in PBS buffer, the animal experiment(test) of Pramipexole dihydrochloride,the in vivo,in vitro and clinical trial test of Pramipexole dihydrochloride,the cell experiment(test) of Pramipexole dihydrochloride,the IC50, EC50 and Affinity of Pramipexole dihydrochloride, please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC5015 Rotigotine Hydrochloride Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine exhibits antiparkinsonian acitivity.
DC3151 Pramipexole dihydrochloride Pramipexole is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM.
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