Remdesivir(GS-5734)
Cat. No.: DC11735
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Chemical Structure
1809249-37-3
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Field of application
Remdesivir is a novel RNA-dependent RNA Polymerase,(RdRp) inhibitor. The purity of remdesivir>99.8%,signal impurity<0.05%.
| Cas No.: |
1809249-37-3 |
| Chemical Name: |
2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[1,2-b]pyridazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate |
| Synonyms: |
GS 5734;GS5734;Remdesivir |
| SMILES: |
C[C@@H](C(=O)OCC(CC)CC)N[P@](=O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@@](C2N3C(C(=NC=N3)N)=CC=2)(C#N)O1)OC1C=CC=CC=1 |
| Formula: |
C27H35N6O8P |
| M.Wt: |
602.57 |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
Remdesivir(GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. |
| In Vitro: |
Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1]. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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