Home > Products > Featured products

Ro 90-7501

  Cat. No.:  DC28150   Featured
Chemical Structure
293762-45-5
For research use only. We do not sell to patients.
We match the best price and quality on market.
Email:order@dcchemicals.com  sales@dcchemicals.com
Tel:+86-021-58447131
Get Quotation Now
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
Ro 90-7501 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces Aβ42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response. Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner. Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 293762-45-5
Chemical Name: Ro 90-7501
Synonyms: [2,5'-Bi-1H-benzimidazol]-5-amine,2'-(4-aminophenyl)-;2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine;RO 90-7501;2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine;GNF-Pf-5510;2′-(4-Aminophenyl)-[2,5′-bi-1H-benzimidazol]-5-amine;HMS3413K16;AKOS001483260;Ro-90-7501;SCHEMBL10002475;HMS3677K16;Ro 90-7501, >=98% (HPLC);CCG-221974;SR-01000389409-1;[2,5'-Bi-1H-benzimidazol]-5-amine, 2'-(4-aminophenyl)-;CHEMBL578741;HMS3262E21;CBDivE_006377;AKOS000635167;CHEBI:93018;Tox21_500670;NCGC00094031-04;DTXSID80356431;NCGC00094031-10;2'-(4-Aminophenyl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-5-amine;NCGC00094031-02;2-[2-(4-AMINOPHENYL)-1H-1,3-BENZODIAZOL-5-YL]-1H-1,3-BENZODIAZOL-5-AMINE;NCGC00094031-06;LP00670;NCGC00094031-01;293762-45-5;NCGC00094031-03;J-017493;HMS3269A19;AB00074940-01;HY-103241;AKOS040742564;SDCCGSBI-0306622.P002;Q27164747;BRD-K58299615-001-02-7;EX-A6609;CS-0026067;NCGC00094031-05;AG-690/09405007;SR-01000389409;NCGC00261355-01;CBChromo1_000149;Cambridge id 5180073;BRD-K58299615-001-03-5;STK367782;2'-(4-aminophenyl)-1H,1'H-2,5'-bibenzimidazol-5-amine;PAGZCEHLFCJSPV-UHFFFAOYSA-N;DA-77508
SMILES: NC1C=CC(C2=NC3C=CC(C4NC5C=C(C=CC=5N=4)N)=CC=3N2)=CC=1
Formula: C20H16N6
M.Wt: 340.38124
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
TITLE DOWNLOAD
MSDS_12205_DC28150_293762-45-5
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
DC44521 Ezeprogind disulfate Ezeprogind (AZP-2006) disulfate is an orally active neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration and is not only aiming at markers such as Abeta protein or tau protein. Ezeprogind disulfate is a potent neuroprotectant and can be used for the research of neurological disorders, including progressive supranuclear palsy (PSP), tauopathies, alzheimer’s and parkinson’s diseases, et al.
DC44520 Ezeprogind Ezeprogind (AZP-2006) is an orally active neurotrophic inducer. Ezeprogind targets all causes of neurodegeneration and is not only aiming at markers such as Abeta protein or tau protein. Ezeprogind is a potent neuroprotectant and can be used for the research of neurological disorders, including progressive supranuclear palsy (PSP), tauopathies, alzheimer’s and parkinson’s diseases, et al.
DC28150 Ro 90-7501 Ro 90-7501 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces Aβ42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response. Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner. Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells.
DC10217 TRx0237 (LMTX) mesylate TRx 0237 (LMTX™) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
DC11301 ALZ-801 ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease.
X
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Site Map|Privacy PolicyCopyright © 2018-2020 All Rights Reserved. Technical Support:KuuJia