Ropivacaine HCL|cas 132112-35-7|supplier DC Chemicals

Cas No.:	132112-35-7
Chemical Name:	(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrate;hydrochloride
Synonyms:	Ropivacaine Hydrochloride Monohydrate; Naropin; Ropivacaine hydrochloride hydrate; Naropin hydrochloride monohydrate; ropivacaine monohydrochloride, (S)-isomer; AL 381; AL-381; LEA 103; LEA-103;
SMILES:	O=C(NC1=C(C)C=CC=C1C)[C@H]2N(CCC)CCCC2.O.Cl
Formula:	C₁₇H₂₉ClN₂O₂
M.Wt:	328.88
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.Ropivacaine is a new long-acting local anesthetic, with vasoconstrictive properties. Ropivacaine given epidurally provided adequate sensory anesthesia and motor block for transurethral surgery. Addition of epinephrine did not provide any significant prolongation of the sensory or motor block, nor any influence upon the sympathetic block [1]. Ropivacaine was metabolized to 2',6'-pipecoloxylidide (PPX), 3'-hydroxyropivacaine (3'-OH Rop), and 4'-hydroxyropivacaine (4'-OH Rop) by hepatic microsomes from human and rat. Ropivacaine N-dealkylation and 3'-hydroxylation activities correlated well with the level of CYP3A4 and 1A2 in human hepatic microsomes, respectively [2].

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101
2018-0101

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