Cas No.: | 489415-96-5 |
Chemical Name: | (2H-Pyrrol-2-one, 1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-) |
Synonyms: | SBC-115076,SBC 115076,SBC115076 |
SMILES: | N(CCCN1CCOCC1)1C(C2C=CN=CC=2)C(C(=O)C2=CC=C(OCC3=CC=CC=C3)C(C)=C2)=C(O)C1=O |
Formula: | C31H33N3O5 |
M.Wt: | 527.61 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds, for the treatment and/or prevention of cardiovascular diseases.Target: PCSK9in vivo: SBC-115076 lowers cholesterol levels in mice that are fed high fat diet. |
References: | [1]. Abdel-Meguid, et al. Anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases |