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SIRT1-IN-1

  Cat. No.:  DC40849   Featured
Chemical Structure
352554-02-0
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More than 5000 active chemicals with high quality for research!
Field of application
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 352554-02-0
Chemical Name: SIRT1-IN-1
Synonyms: 1H-Carbazole-1-carboxamide, 2,3,4,9-tetrahydro-6-methyl-;SIRT1-IN-1;6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide;Oprea1_169494;HMS1517B20;G12668;CHEMBL115600;CS-0120561;(6-Methyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)formamide;SR-01000001381-2;HY-136199;SMR000041923;352554-02-0;SCHEMBL8244015;MS-23295;SR-01000001381;DA-77859;HMS2582N08;MLS000036457;AKOS021714064;ChemDiv3_015530;STL336698;BDBM50178773;HMS3448P13
SMILES: CC1=CC2=C(C=C1)NC3=C2CCCC3C(=O)N
Formula: C14H16N2O
M.Wt: 228.29
Purity: >98%
Sotrage: Powder-20°C3 years4°C2 yearsIn solvent-80°C 6 months-20°C1 month
MSDS
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MSDS_23862_DC40849_352554-02-0
COA
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Cat. No. Product name Field of application
DC73350 JYQ-42 JYQ-42 is a potent, selective SIRT6 allosteric inhibitor, effectively inhibits SIRT6 deacetylation with IC50 of 2.33 uM, inhibits the deacetylation activity of SIRT6 in pancreatic cancer cell lines.
DC71745 Sirtuin modulator 2 Sirtuin modulator 2 (Compound 132) is a sirtuin modulator with an ED50 equal or less than 50 μM.
DC71744 MIND4-19 MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease.
DC40849 SIRT1-IN-1 SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity.
DC40782 SIRT7 inhibitor 97491 SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway..
DC11213 E1231 E1231 (E-1231) is a small molecule SIRT1 activator with EC50 of 0.83 uM, interactes with recombinant human SIRT1 protein and deacetylated liver X receptor-alpha (LXRα).
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