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SN 2

  Cat. No.:  DC9622  
Chemical Structure
823218-99-1
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More than 5000 active chemicals with high quality for research!
Field of application
SN 2 is a novel and potent small molecule activator of TRPML3 with EC50 of 1.13 uM.
Cas No.: 823218-99-1
Synonyms: SN2;SN-2
SMILES: CC(C=C(C)C=C1C)=C1C2=NOC3C2C4CC3CC4
Formula: C17H21NO
M.Wt: 255.3547
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: SN 2 is a novel and potent small molecule activator of TRPML3 with EC50 of 1.13 uM. Compounds SF21, SF-41, and SN-2 elicited a much more rapid increase than the other compounds, with SF-33 and SF 51 displaying the slowest kinetics. SN-2 had a similar synergistic effect, also reaching up-to 10-fold enhancement of the combined response when compared with the individual responses, reaching average current densities of up to 3 nA/pF at -80 mV.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC46466 Dihydrocapsiate Dihydrocapsiate, as a compound of capsinoid family, is an orally active TRPV1 agonist. Dihydrocapsiate can be used for the research of metabolism disease.
DC46465 Capsiate Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1.
DC45871 Methyl kakuol Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM.
DC45849 GSK2332255B GSK2332255B is a potent, selective TRPC3 and TRPC6 antagonist with IC50s of 5 nM and 4 nM for rat TRPC3 and rat TRPC6. GSK2332255B shows ≥100-fold selectivity for TRPC3/6 over other calcium-permeable channels.
DC45289 OptoBI-1 OptoBI-1 is a photochromic TRPC3 agonist, which asts as a photopharmacological tool to control of neuronal firing.
DC45288 AMG2850 AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist.
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