| DC7028 |
SB242235
|
SB-242235 is a potent and selective p38 MAP kinase inhibitor with IC50 of 1.0 uM. |
| DC9300 |
TA-02
|
TA-02 induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction. Potently inhibits p38α, CK1δ and CK1ε (IC50 values are 20, 32 and 32 nM respectively). |
| DC7946 |
SKF-86002
|
SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM). |
| DC1004 |
SB-203580
|
SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM and blocks PKB phosphorylation with IC50 of 3-5 μM. |
| DC7807 |
SB 239063
|
SB 239063 is a potent and selective p38 MAPK inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580. |
| DC2097 |
SB202190
|
SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway. |
| DC5095 |
PD169316
|
PD169316 is a potent and selective p38 MAP kinase inhibitor |
| DC9681 |
Pamapimod（R-1503）
|
Pamapimod（R-1503）is a novel p38 MAP kinase inhibitor. |
| DC8630 |
Ralimetinib 2MsOH(LY2228820)
|
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38αMAPK and p38βMAPK were 7 nM and 3 nM, respectively). |
| DC7836 |
Doramapimod (BIRB-796)
|
BIRB 796 (Doramapimod) is a highly selective p38α MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKCα/β/γ. |
