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TCMDC-135051 hydrochloride

  Cat. No.:  DC40362  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
TCMDC-135051 hydrochloride is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 hydrochloride prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 hydrochloride has antiparasiticidal activity (EC50=320 nM).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.:
Chemical Name: TCMDC-135051 hydrochloride
SMILES: O=C(O)C1=CC=C(C2=C3C(NC(C4=C(OC)C=CC(CN(CC)CC)=C4)=C3)=NC=C2)C=C1C(C)C.[H]Cl
Formula: C29H34ClN3O3
M.Wt: 508.05
Sotrage: Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month
MSDS
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COA
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Cat. No. Product name Field of application
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DC47403 TCMDC-136230 TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
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DC47401 Antileishmanial agent-1 Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM).
DC47400 BRD5018 BRD5018 is an antimalarial agent.
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DC47107 14-Deoxy-11-oxoandrographolide 14-Deoxy-11-oxoandrographolide is an antileishmanial agent. 14-Deoxy-11-oxoandrographolide inhibits the replication of heal chikungunya virus (CHIKV) and can be used for CHIKV infection research.
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