COX-1 Inhibitor IV(TFAP)

  Cat. No.:  DC11263   Featured
Chemical Structure
1011244-68-0
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More than 5000 active chemicals with high quality for research!
Field of application
The COX-1 Inhibitor IV, TFAP controls the biological activity of COX-1.
Cas No.: 1011244-68-0
Chemical Name: N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
SMILES: C1=CC(=CC=C1C(=O)NC2=NC=C(C=C2)N)C(F)(F)F
Formula: C13H10F3N3O
M.Wt: 281.23
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.
Target: COX-1:0.8 μM (IC50) Human Endogenous Metabolite
In Vitro: TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM, while that against COX-2 is over 200 μM.
References: [1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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