THI0019|CAS 1378532-99-0|DC Chemicals

Cas No.:	1378532-99-0
Chemical Name:	THI0019
Synonyms:	THI0019
SMILES:	C1(=CC=CS1)CN(CC1=CC=CS1)C(OC[C@H](CCCC)NC(=O)N[C@@H](CC(OC)=O)C1C=C2C(=CC=1)OCO2)=O
Formula:	C₂₉H₃₅N₃O₇S₂
M.Wt:	601.73
Purity:	>98%
Sotrage:	Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month

MSDS

COA

Cat. No.	Product name	Field of application
DC73236	GSK3335103	GSK3335103 is a highly potent and orally bioavailable nonpeptidic αvβ6 integrin inhibitor with pIC50 of 8.0. GSK3335103 shows high desirable oral pharmacokinetic profiles in rat, dog, and minipig, with low to moderate clearance, moderate volumes of distributio, high to complete oral bioavailabilities and high solubility in all physiological media.
DC40247	THI0019	THI0019 is a potent integrin α4β1 (VLA-4) agonist with an EC50 range of 1-2 μM. THI0019 induces stem/progenitor cells adhesion. THI0019 also regulates adhesion mediated by α4β7, α5β1 and αLβ2.
DC9487	Arg-Gly-Asp-Ser	Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS