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TSHR antagonist S37a

Cat. No.: DC28610

Chemical Structure

2143452-20-2

For research use only. We do not sell to patients.

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Field of application

TSHR antagonist S37a is a highly selective thyrotropin receptor (TSHR) antagonist, with potential for the treatment of Graves' orbitopathy.

Cas No.:	2143452-20-2
SMILES:	O=C(N1)SC([C@H]2C3=CC=CC=C3)=C1S[C@@]([C@@]2([H])[C@@]4([H])[C@@]56[H])([H])[C@](C4)([H])[C@]6([H])C(N(C7=CC=CC=C7)C5=O)=O
Formula:	C₂₅H₂₀N₂O₃S₂
M.Wt:	460.57
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

TITLE	DOWNLOAD
MSDS_12662_DC28610_2143452-20-2

COA

LOT NO.	DOWNLOAD

Cat. No.	Product name	Field of application
DC28999	NCGC00229600	NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease.
DC28611	TSHR antagonist S37	TSHR antagonist S37 is a selective and competitive thyrotropin receptor (TSHR) antagonist. TSHR antagonist S37 is the racemate of TSHR antagonist S37a.
DC28610	TSHR antagonist S37a	TSHR antagonist S37a is a highly selective thyrotropin receptor (TSHR) antagonist, with potential for the treatment of Graves' orbitopathy.

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