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| Cas No.: | 161832-65-1 |
| Chemical Name: | 1-[(8R)-5-(4-aminophenyl)-8-methyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-7-yl]ethanone |
| Synonyms: | Ampanel, Kinampa, Talampanel (INN), GYKI 53773, AC1L4UWP, AC1Q5KPR |
| SMILES: | C[C@@H]1CC2=C(C=C3OCOC3=C2)C(C4=CC=C(N)C=C4)=NN1C(C)=O |
| Formula: | C19H19N3O3 |
| M.Wt: | 337.372 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED). |
| In Vivo: | Talampanel reduces motoneuronal calcium in a mouse model of ALS, but its effi cacy declines as the disease progresses, suggesting that medication initiation in the earlier stages of the disease might be more effective. [2] |
| In Vitro: | Talampanel is a glutamate receptor inhibitor with anti-seizure activity. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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