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Teglicar

  Cat. No.:  DC7515   Featured
Chemical Structure
250694-07-6
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More than 5000 active chemicals with high quality for research!
Field of application
Teglicar, in vitro and in animal models, reduces gluconeogenesis and improves glucose homeostasis, refreshing the interest in selective and reversible L-CPT1 inhibition as a potential antihyperglycemic approach.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 250694-07-6
Chemical Name: Teglicar
Synonyms: 1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-, inner salt,(2R)-;4-trimethylammonio-3-((tetradecylcarbamoyl)amino)butyrate;1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-, inner salt,(2...;3-(tetradecylcarbamoylamino)-4-(trimethylazaniumyl)butanoate;Teglicar;8V3VQ6HMII;(3R)-3-(tetradecylcarbamoylamino)-4-(trimethylazaniumyl)butanoate;Teglicar [INN];4-trimethylammonio-TDCAB;(3r)-3-{[(Tetradecylamino)carbonyl]amino}-4-(Trimethylammonio)butanoate;[3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimethyl-ammonium;st1326;BDBM50122839;Q27271060;ST1326; (R)-N-TETRADECYLCARBAMOYL-AMINOCARNITINE;(3R)-3-((Tetradecylaminocarbonyl)amino)-4-(trimethylazaniumyl)butanoate;GTPL12976;3-(TETRADECYLCARBAMOYLAMINO)-4-TRIMETHYLAMMONIO-BUTANOATE;250694-07-6;AKOS027323786;MS-26779;(3R)-3-[(TETRADECYLCARBAMOYL)AMINO]-4-(TRIMETHYLAMMONIO)BUTANOATE;ST-1326;SCHEMBL3685373;CHEMBL1231506;HY-16482;CHEMBL106227;CS-0006357;ST1326, (R)-3-(3-tetradecylureido)-4-(trimethylammonio)butanoate, powder;compound 17 [Giannessi et al., 2003];UNII-8V3VQ6HMII
SMILES: O=C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])[C@]([H])(C([H])([H])C(=O)[O-])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
Formula: C22H45N3O3
M.Wt: 399.6110
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1].
Target: IC50: L-CPT1[1]
References: [1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC7515 Teglicar Teglicar, in vitro and in animal models, reduces gluconeogenesis and improves glucose homeostasis, refreshing the interest in selective and reversible L-CPT1 inhibition as a potential antihyperglycemic approach.
DC10581 Succinobucol（AGI 1067) Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects.
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