UNC6852

  Cat. No.:  DC28688   Featured
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
UNC6852 is a selective rolycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand, with an IC50 of 247 nM for EED.
Cas No.:
Chemical Name: UNC6852
Synonyms: UNC 6852;UNC-6852;UNC6852
SMILES: O=C(NCCCC(=O)N[C@@H](C(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(C2SC=NC=2C)=CC=1)C1C=CC(C2C3=NN=CN3C(NCC3OC=CC=3)=NC=2)=CC=1
Formula: C43H48N10O6S
M.Wt: 832.969627380371
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC28688 UNC6852 UNC6852 is a selective rolycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand, with an IC50 of 247 nM for EED.
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