WAY181187.HCl（WAY-181,187）
Cat. No.: DC9668
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Chemical Structure
554403-49-5
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Field of application
WAY-181187 is a potent and selective 5-HT6 receptor agonist. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%).
| Cas No.: |
554403-49-5 |
| Synonyms: |
WAY-181187; WAY 181187; WAY181187 |
| SMILES: |
NCCC1=CN(S(=O)(C2=C(Cl)N=C3SC=CN32)=O)C4=C1C=CC=C4 |
| Formula: |
C15H13ClN4O2S2 |
| M.Wt: |
380.87 |
| Purity: |
>98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
WAY-181187 is a potent and selective 5-HT6 receptor agonist. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%). In the rat frontal cortex, acute administration of WAY-181187 (3-30 mg/kg, subcutaneous (s.c.)) significantly increased extracellular GABA concentrations without altering the levels of glutamate or norepinephrine. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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