ZM447439 (ZM-447439)|supplier DC Chemicals

Cas No.:	331771-20-1
Chemical Name:	N-(4-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-ylamino)phenyl)benzamide
Synonyms:	ZM 447439
SMILES:	O=C(NC1=CC=C(NC2=C(C(C=C3OCCCN4CCOCC4)=NC=N2)C=C3OC)C=C1)C5=CC=CC=C5
Formula:	C₂₉H₃₁N₅O₄
M.Wt:	513.59
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

ZM447439 (ZM) is a potent and selective inhibitor of aurora-A and -B kinase with putative anti-tumoral activity. ZM induced apoptosis in a concentration- and time-dependent manner. For the detailed information about the solubility of ZM447439 (ZM-447439) in water, the solubility of ZM447439 (ZM-447439) in DMSO, the solubility of ZM447439 (ZM-447439) in PBS buffer, the animal experiment（test） of ZM447439 (ZM-447439),the in vivo,in vitro and clinical trial test of ZM447439 (ZM-447439),the cell experiment（test） of ZM447439 (ZM-447439),the IC50, EC50 and Affinity of ZM447439 (ZM-447439), please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC1084	ZM447439 (ZM-447439)	ZM-447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively.
DC11370	TAK-901	TAK-901 is a non-selective Aurora kinase inhibitor (IC50s = 3.1, 10, and 4.2 nM for Aurora A, B, and C, respectively).