ZM447439 (ZM-447439)

  Cat. No.:  DC1084   Featured
Chemical Structure
331771-20-1
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Field of application
ZM-447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively.
Cas No.: 331771-20-1
Chemical Name: ZM-447439
Synonyms: N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide;ZM 447439;ZM-447439;N-(4-((6-Methoxy-7-(3-Morpholinopropoxy)quinazolin-4-yl)aMino)phenyl)benzaMide;N-(4-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-ylamino)phenyl)benzamide;ZM447439 (ZM-447439);BenzaMide, N-[4-[[6-Methoxy-7-[3-(4-Morpholinyl)propoxy]-4-quinazolinyl]aMino]phenyl]-
SMILES: O=C(NC1=CC=C(NC2=C(C(C=C3OCCCN4CCOCC4)=NC=N2)C=C3OC)C=C1)C5=CC=CC=C5
Formula: C29H31N5O4
M.Wt: 513.58754
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: ZM447439 (ZM) is a potent and selective inhibitor of aurora-A and -B kinase with putative anti-tumoral activity. ZM induced apoptosis in a concentration- and time-dependent manner. For the detailed information about the solubility of ZM447439 (ZM-447439) in water, the solubility of ZM447439 (ZM-447439) in DMSO, the solubility of ZM447439 (ZM-447439) in PBS buffer, the animal experiment(test) of ZM447439 (ZM-447439),the in vivo,in vitro and clinical trial test of ZM447439 (ZM-447439),the cell experiment(test) of ZM447439 (ZM-447439),the IC50, EC50 and Affinity of ZM447439 (ZM-447439), please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC1084 ZM447439 (ZM-447439) ZM-447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively.
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