AZD0011|CAS 2374807-41-5|DC Chemicals

Cas No.:	2374807-41-5
Chemical Name:	AZD0011
Formula:	C₁₄H₂₈BN₃O₅
M.Wt:	329.2
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC74620	OATD-02	OATD-02 is an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and 2. OATD-02 is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 abolishes tumor immunosuppression induced by both arginases. OATD-02 can be used for melanoma study.
DC73715	AZD0011-PL	AZD0011-PL is a highly potent Arginase (ARG) inhibitor with IC50 of 7/15 nM for ARG1/2, respectively.
DC73714	AZD0011	AZD0011 (AZD-0011) a novel peptidic boronic acid prodrug of AZD0011-PL, highly potent and orally available Arginase (ARG) inhibitor with IC50 of 404/308 nM for ARG1/2, respectively.
DC48211	ARG1-IN-1	ARG1-IN-1 is a human arginase 1 inhibitor with an IC50 of 29 nM.